ARIES: A Scalable Multi-Agent Orchestration Framework for Real-Time Epidemiological Surveillance and Outbreak Monitoring

February 09, 2026

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Title: ARIES: A Scalable Multi-Agent Orchestration Framework for Real-Time Epidemiological Surveillance and Outbreak Monitoring
ArXiv ID: 2601.01831
Date: 2026-01-05
Authors: Aniket Wattamwar, Sampson Akwafuo

📝 Abstract

Global health surveillance is currently facing a challenge of Knowledge Gaps. While general-purpose AI has proliferated, it remains fundamentally unsuited for the highstakes epidemiological domain due to chronic hallucinations and an inability to navigate specialized data silos. This paper introduces ARIES (Agentic Retrieval Intelligence for Epidemiological Surveillance), a specialized, autonomous multi-agent framework designed to move beyond static, disease-specific dashboards toward a dynamic intelligence ecosystem. Built on a hierarchical command structure, ARIES utilizes GPTs to orchestrate a scalable swarm of sub-agents capable of autonomously querying World Health Organization (WHO), Center for Disease Control and Prevention (CDC), and peer-reviewed research papers. By automating the extraction and logical synthesis of surveillance data, ARIES provides a specialized reasoning that identifies emergent threats and signal divergence in near real-time. This modular architecture proves that a task-specific agentic swarm can outperform generic models, offering a robust, extensible for next-generation outbreak response and global health intelligence.

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ARIES: A Scalable Multi-Agent Orchestration Framework for Real-Time Epidemiological Surveillance and Outbreak Monitoring

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