Agreeing to disagree, some ironies, disappointing scientific practice and a call for better: reply to <<The poor performance of TMM on microRNA-Seq>>

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📝 Original Info

  • Title: Agreeing to disagree, some ironies, disappointing scientific practice and a call for better: reply to «The poor performance of TMM on microRNA-Seq»
  • ArXiv ID: 1305.6202
  • Date: 2013-06-11
  • Authors: Researchers from original ArXiv paper

📝 Abstract

This letter is a response to a Divergent Views article entitled <> (Garmire and Subramaniam 2013), which was a response to our Divergent Views article entitled <> (Zhou et al. 2013). Using reproducible code examples, we showed that they incorrectly used our normalization method and highlighted additional concerns with their study. Here, I wish to debunk several untrue or misleading statements made by the authors (hereafter referred to as GS) in their response. Unlike GSs, my claims are supported by R code, citations and email correspondences. I finish by making a call for better practice.

💡 Deep Analysis

Deep Dive into Agreeing to disagree, some ironies, disappointing scientific practice and a call for better: reply to <>.

This letter is a response to a Divergent Views article entitled «The poor performance of TMM on microRNA-Seq» (Garmire and Subramaniam 2013), which was a response to our Divergent Views article entitled «miRNA-seq normalization comparisons need improvement» (Zhou et al. 2013). Using reproducible code examples, we showed that they incorrectly used our normalization method and highlighted additional concerns with their study. Here, I wish to debunk several untrue or misleading statements made by the authors (hereafter referred to as GS) in their response. Unlike GSs, my claims are supported by R code, citations and email correspondences. I finish by making a call for better practice.

📄 Full Content

This letter is a response to a Divergent Views article entitled <> (Garmire and Subramaniam 2013), which was a response to our Divergent Views article entitled <> (Zhou et al. 2013). Using reproducible code examples, we showed that they incorrectly used our normalization method and highlighted additional concerns with their study. Here, I wish to debunk several untrue or misleading statements made by the authors (hereafter referred to as GS) in their response. Unlike GSs, my claims are supported by R code, citations and email correspondences. I finish by making a call for better practice.

Reference

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